You are here:Home
»
Antibodies
»
Abs to Ribosomal Proteins
»
Anti -Ribosomal Protein S6, phosphorylated (Ser235) (RPS6, 40S Ribosomal Protein S6, Phosphoprotein NP33, OK/SW-cl.2)
Anti -Ribosomal Protein S6, phosphorylated (Ser235) (RPS6, 40S Ribosomal Protein S6,
Phosphoprotein NP33, OK/SW-cl.2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS6 is a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. | | | Catalog # | R2031-30N | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot:1:500-1:1,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to human S6 Ribosomal protein around the phosphorylation site of serine 235 (R-L-SP-S-L). | | Specificity | Recognizes human Ribosomal Protein S6, phosphorylated at (Ser235). Species Cross-Reactivity: mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
