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You are here:Home » Antibodies » Abs to Ribosomal Proteins » Anti -Ribosomal Protein S6, phosphorylated (Ser235, Ser236) (40S Ribosomal Protein S6, RPS6, RPS-6, Air8, DS6, Hemocytes Enlarged, Hen, I(1)AIR8, Lethal (1) Haemocytes Enlarged, Lethal Aberrant Immune Response 8, Lethal(1)abberant Immune Response[8], Phosphopro

Anti -Ribosomal Protein S6, phosphorylated (Ser235, Ser236) (40S Ribosomal Protein S6,
RPS6, RPS-6, Air8, DS6, Hemocytes Enlarged, Hen, I(1)AIR8, Lethal (1) Haemocytes Enlarged,
Lethal Aberrant Immune Response 8, Lethal(1)abberant Immune Response[8], Phosphopro

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
40S ribosomal protein S6 (also known as RPS6) is a ~31kD substrate of p70 S6 kinase (p70S6K) and a major component of translational machinery involved in protein synthesis, cell growth, proliferation, and metabolism. RPS6 undergoes phosphorylation on multiple serines in the carboxyl terminal region in the order 236-->235-->240-->244-->247, due to the positions of these amino acid residues on the alpha-helix. Hyperphosphorylation of RPS6 stimulates protein synthesis that mediates progression through the cell cycle.
Catalog #R2031-31A1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:2,500-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, which represented a portion of human Ribosomal Protein S6 (GeneID 6194) around serine 235 and serine 236 according to the numbering given in entry NP_001001.2.
SpecificityRecognizes human Ribosomal Protein S6, phosphorylated at Ser235 and Ser236.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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