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You are here:Home » Antibodies » Abs to Ribosomal Proteins » Anti -Ribosomal Protein S6, phosphorylated (Ser235, Ser236) (40S Ribosomal Protein S6, RPS6, RPS-6, Air8, DS6, Hemocytes Enlarged, Hen, I(1)AIR8, Lethal (1) Haemocytes Enlarged, Lethal Aberrant Immune Response 8, Lethal(1)abberant Immune Response[8], Phosphopro

Anti -Ribosomal Protein S6, phosphorylated (Ser235, Ser236) (40S Ribosomal Protein S6,
RPS6, RPS-6, Air8, DS6, Hemocytes Enlarged, Hen, I(1)AIR8, Lethal (1) Haemocytes Enlarged,
Lethal Aberrant Immune Response 8, Lethal(1)abberant Immune Response[8], Phosphopro

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC
Ribosomal protein S6 (RPS6) belongs to S6E family of ribosomal proteins and it is involved in the control of cell growth and proliferation via selective translation (1). It is a major substrate of Ribosomal Protein S6 Kinase (RSK) in the eukaryote ribosomes.During translation, it regulates the translation of any RNA which contains 5í terminal oligopyrimidine sequence (5íTOP) (2). 5íTOP encodes proteins for cell cycle progression, ribosomal proteins, and elongation factors. The phospholyation of RPS6 has been linked to increase in selective 5íTOP translation.The major phospholyation sites RPS6 includes Ser235, 236, 240, and 244 (2). The phospholyation on RPS6 is stimulated by growth factors, tumor promoting agents, and mitogens.During growth
arrest, RPS6 is dephoshorylated (3).
Applications:
Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Catalog #R2031-31A3
Recommended DilutionWestern Blot: 1:10,000-1:20,0000
Immunoprecipitation: 1:30
Immunohistochemistry: 1:100-1:250
Immunocytochemistry: 1:100-1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H502
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-Glycine (pH 7.4), 0.15M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding serine 235/236 of human S6 Ribosomal Protein.
SpecificityRecognizes human S6 Ribosomal Protein when phosphorylated at Ser235 and Ser236.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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