Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Protein Kinases, Ribosomal » Anti -RPS6KB1 (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kinase I, Serine/threonine-pr

Anti -RPS6KB1 (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal
Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase
alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kinase I,
Serine/threonine-pr

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
p70 S6 kinase (p70S6K, p85S6K) or ribosomal protein S6 kinase has 2 isoforms both of which are monomers. The first isoform, p70, has a predicted molecular mass of 56kD and an apparent molecular mass (SDS-PAGE) of 70kD. The second isoform, p85 which contains 23 extra residues at the N-terminus, is generated by alternative splicing and has a predicted molecular mass of 59kD and an apparent molecular mass of 85kD. Serine phosphorylation of the S6 kinase is required for its activation, and this is accompanied by mobility shift in the migration of this 65kD kinase on SDA polyacrylamide gels to 70kD. Phosphorylation of the S6 protein has been linked with increased rates of initiation of protein synthesis with certain mRNA transcripts.
Catalog #R2031-38B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: MISKRPEHLRMNL, representing the C-Terminus of the human protein (residues 490-502), according to NP_003152.
SpecificitySpecies Crossreactivity: Human. Expected to crossreact with Mouse (100% identity with immunogen), Xenopus laevis (100% identity with immunogen), bovine (100% identity with immunogen) and Rabbit (100% identity with immunogen) due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRibosomal Protein S6 Kinase 70kDa Polypeptide 1, EC=2.7.11.1, p70-alpha, p70(S6K)-alpha, PS6K, S6K1


External Links