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You are here:Home » Antibodies » Abs to Protein Kinases, Ribosomal » Anti -RPS6KB1 (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kinase I, Serine/threonine-pr

Anti -RPS6KB1 (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal
Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase
alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kinase I,
Serine/threonine-pr

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
p70 S6 kinase (p70S6K, p85S6K) or ribosomal protein S6 kinase has 2 isoforms both of which are monomers. The first isoform, p70, has a predicted molecular mass of 56kD and an apparent molecular mass (SDS-PAGE) of 70kD. The second isoform, p85 which contains 23 extra residues at the N-terminus, is generated by alternative splicing and has a predicted molecular mass of 59kD and an apparent molecular mass of 85kD. Serine phosphorylation of the S6 kinase is required for its activation, and this is accompanied by mobility shift in the migration of this 65kD kinase on SDA polyacrylamide gels to 70kD. Phosphorylation of the S6 protein has been linked with increased rates of initiation of protein synthesis with certain mRNA transcripts.
Catalog #R2031-38C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationAs reported
FormAs reported
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide, which represented a portion of the C-terminus of human ribosomal protein S6 kinase,70 kDa. (LocusLink ID 6197).
SpecificitySpecific for human p70S6. Mouse and human have identical sequence as rat for the immunizing peptide. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRibosomal Protein S6 Kinase 70kDa Polypeptide 1, EC=2.7.11.1, p70-alpha, p70(S6K)-alpha, PS6K, S6K1


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