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You are here:Home » Antibodies » Abs to Protein Kinases, Ribosomal » Anti -RPS6KB1, phosphorylated (Thr389) (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kina

Anti -RPS6KB1, phosphorylated (Thr389) (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1,
S6K1, 70kD Ribosomal Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase
alpha, p70 S6 Kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kina

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
p70 S6 Kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. P70 S6 Kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5-oligopyrimidine tract mRNAs. A second isoform, p85 S6 Kinase, is derived from the same gene and is identical to p70 S6 Kinase except for 23 extra residues at the N-terminus that encode a nuclear localizing signal.
Catalog #R2031-38P
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormPBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide
PurityPurified by immunoaffinity chromatography.
SpecificityThis antibody detects p70 S6 Kinase only when phosphorylated at Thr389; and detects p85 S6 Kinase only when phosphorylated at the analogous site (Thr412). Species Crossreactivity: Human, Rat and Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRibosomal Protein S6 Kinase 70kDa Polypeptide 1, EC=2.7.11.1, p70-alpha, p70(S6K)-alpha, PS6K, S6K1


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