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Anti -Ricin communis (RCA I, Castor bean) (Biotin)
Anti -Ricin communis (RCA I, Castor bean) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E |
|
| Ricin is a protein toxin that is readily produced from castor beans (Lectin Ricinus communis) which inhibits protein synthesis. Red blood cells agglutinate due to the presence of RCA (Ricinus communis agglutinin) a potent cytotoxin but a weak hemagglutinin. | | | Ricin and RCA are synthesized in the endosperm cells of maturing seeds, and are stored in an organelle called the "protein body", a vacuolar compartment. When the mature seed germinates, the toxins are destroyed by hydrolysis within a few days. | | | Ricin can be targeted to specific cells, such as cancer cells, by conjugating the RTA subunit to antibodies or growth factors that preferentially bind the unwanted cells. These immunotoxins have worked very well for in vitro applications, e.g. bone marrow transplants. Although they have not worked very well in many in vivo situations, progress in this area of research shows promise for the future. | | | Catalog # | R2031-50C | | Applications | Suitable for use in ELISA, Immunodiffusion and IEP. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide. Labeled with Biotin. | | Purity | Purified by affinity chromatography. | | Immunogen | Ricin communis (RCA1, Castor bean). | | Specificity | Recognizes Ricin communis. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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