Anti -Ring Finger Protein 34 (RNF34, Caspase Regulator CARP1, Caspases 8 and 10-associated
RING Finger Protein 1, CARP-1, FLJ21786, FYVE-RING Finger Protein Momo, hRFI, Human RING
Finger Homologous to Inhibitor of Apoptosis Protein hRFI, RFI, RIFF, Ring Finger
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
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| Ring Finger is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers. | | | Catalog # | R2031-88B | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilutions | ELISA: 1:800-1:4000 | | Western Blot: 1:100-1:600. Detects a band at ~42kD | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide. | | Purity | Purified by affinity chromatography | | Immunogen | Recombinant protein corresponding to aa1-373 of human RFI. Species Sequence Homology: bovine, New World primate, mouse, canine and rat | | Specificity | Recognizes human Ring Finger Protein 34. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Ring Finger Protein 34 (RNF34, Caspase Regulator CARP1, Caspases 8 and 10-associated RING Finger Protein 1, CARP-1, FLJ21786, FYVE-RING Finger Protein Momo, hRFI, Human RING Finger Homologous to Inhibitor of Apoptosis Protein hRFI, RFI, RIFF, Ring Finger |
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