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You are here:Home » Antibodies » Abs to Enzymes, Polymerase » Anti -RNA Polymerase II Subunit 5 (RMP5, Pol II, Pol2)

Anti -RNA Polymerase II Subunit 5 (RMP5, Pol II, Pol2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP
The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Catalog #R2039-21B
Alternate Names anti-RMP antibody, anti-RNA polymerase II antibody, anti-subunit 5 (RPB5)-mediating protein antibody, anti-URI antibody, anti-unconventional prefoldin RPB5 interactor antibody, anti-C19orf2 antibody, anti-chromosome 19 open reading frame antibody, anti-NNX3 antibody
Applications:
Suitable for use in ELISA, Western Blotting, Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blotting: 1:2000-1:10,000
Immunoprecipitation: 2-5ug/ml lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in tris-buffered saline, 0.1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a region between aa458 and 508.
SpecificityRecognizes human RMP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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