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You are here:Home » Molecular Biology » MB-Cloning-Enzymes » RNA Polymerase II, DNA Directed, Polypeptide C, 33kD (POLR2C, RNA Polymerase II Subunit 3) Recombinant

RNA Polymerase II, DNA Directed, Polypeptide C, 33kD (POLR2C, RNA Polymerase II Subunit 3)


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Eukaryotic DNA-dependent RNA polymerase II (or B) is composed of 10-14 polypeptides ranging from 220-10kD. Polypeptide C is the third largest subunit of RNA polymerase II. Polymerase II is responsible for synthesizing messenger RNA in eukaryotes. It contains a cysteine rich region. It exists as a heterodimer with another polymerase subunit. These two subunits form a core subassembly unit of the polymerase. Two transcript varients, differing only in the 3’UTR and encode the same protein. A pseudogene has been identified on chromosome 21.
Catalog #R2039-25
ApplicationsSuitable for use in Western Blot, MS, ELISA as an antigen, ligand, or assay standard. Other applications not tested.
Recommend DilutionsOptimal dilutions to be determined by researcher.
Storage and Stability May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
Important note This recombinant enzyme has NOT been tested with regard to biological activity.
SourceHuman, recombinant expressed in E. coli
PurityHighly purified ( 95%)
Protein GI Number14702173
Protein Accession NumberNP_002685
DomainFull-length (aa1-275)
MW31.6kD (Calculated)
Tag/Fusion PartnerT7 Tag
Quality ControlSDS-PAGE
FormSupplied as a liquid in10mM Tris, pH 8.0, 0.1% Triton X100, 0.002% sodium azide.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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