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RNA Polymerase II, DNA Directed, Polypeptide C, 33kD (POLR2C, RNA Polymerase II Subunit 3) Recombinant
RNA Polymerase II, DNA Directed, Polypeptide C, 33kD (POLR2C, RNA Polymerase II Subunit 3) Recombinant
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| Eukaryotic DNA-dependent RNA polymerase II (or B) is composed of 10-14 polypeptides ranging from 220-10kD. Polypeptide C is the third largest subunit of RNA polymerase II. Polymerase II is responsible for synthesizing messenger RNA in eukaryotes. It contains a cysteine rich region. It exists as a heterodimer with another polymerase subunit. These two subunits form a core subassembly unit of the polymerase. Two transcript varients, differing only in the 3’UTR and encode the same protein. A pseudogene has been identified on chromosome 21. | | | Catalog # | R2039-25 | | Applications | Suitable for use in Western Blot, MS, ELISA as an antigen, ligand, or assay standard. Other applications not tested. | | Recommend Dilutions | Optimal dilutions to be determined by researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | Important note | This recombinant enzyme has NOT been tested with regard to biological activity. | | Source | Human, recombinant expressed in E. coli | | Purity | Highly purified ( 95%) | | Protein GI Number | 14702173 | | Protein Accession Number | NP_002685 | | Domain | Full-length (aa1-275) | | MW | 31.6kD (Calculated) | | Tag/Fusion Partner | T7 Tag | | Quality Control | SDS-PAGE | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in10mM Tris, pH 8.0, 0.1% Triton X100, 0.002% sodium azide. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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