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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -Ring Finger Protein 8 (Ring Finger Protein (C3HC4 Type) 8, RNF8, C3HC4 Type Zinc Finger Protein, E3 Ubiquitin Protein Ligase RNF8, FLJ12013, KIAA0646, UBC13/UEV-interacting Ring Finger Protein)
Anti -Ring Finger Protein 8 (Ring Finger Protein (C3HC4 Type) 8, RNF8, C3HC4 Type Zinc Finger Protein, E3 Ubiquitin Protein Ligase RNF8, FLJ12013, KIAA0646, UBC13/UEV-interacting Ring Finger Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Results suggest a novel function of RNF8 as a regulator of RXR alpha-mediated transcriptional activity through interaction between their respective N-terminal regions. | | | Catalog # | R2993-81M | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide GEPGFFVTGDRAG, representing the N-Terminus of the human protein (residues 2-14), according to NP_003949. | | Specificity | Species Crossreactivity: Reacts with Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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