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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -Ring Finger Protein 8 (Ring Finger Protein (C3HC4 Type) 8, RNF8, C3HC4 Type Zinc Finger Protein, E3 Ubiquitin Protein Ligase RNF8, FLJ12013, KIAA0646, UBC13/UEV-interacting Ring Finger Protein)

Anti -Ring Finger Protein 8 (Ring Finger Protein (C3HC4 Type) 8, RNF8, C3HC4 Type Zinc
Finger Protein, E3 Ubiquitin Protein Ligase RNF8, FLJ12013, KIAA0646,
UBC13/UEV-interacting Ring Finger Protein)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Results suggest a novel function of RNF8 as a regulator of RXR alpha-mediated transcriptional activity through interaction between their respective N-terminal regions.
Catalog #R2993-81M
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide GEPGFFVTGDRAG, representing the N-Terminus of the human protein (residues 2-14), according to NP_003949.
SpecificitySpecies Crossreactivity: Reacts with Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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