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Anti -Rotavirus, ICP, Late Structural Virion Antigens
Anti -Rotavirus, ICP, Late Structural Virion Antigens
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Purified |
E B IH IF |
|
| Rotaviruses, members of the family Reoviridae, are a major cause of diarrhea in young mammals. Human rotaviruses, the major etiological agents of severe infantile diarrhea worldwide, display very diverse and complex serotypic specificities. Rotaviruses are 70nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection. Therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence. | | | Catalog # | R3000-01A | | Applications | Suitable for use in Indirect Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Indirect Immunofluorescence: ~1:250 | | Western Blot: Unboiled samples in 1mM DDT and 2% SDS only. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Concentration | Not Determined | | Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. | | Purity | Purified | | Immunogen | Bovine (Nebraska Calf Diarrhea Virus) | | Specificity | Recognizes Rotavirus (ICP’s and late structural virion antigens). Species Crossreactivity: >90% reactive with human rotaviruses. Non-reactive with HEp-2 cells and WI-38 cells by indirect immunofluorescence. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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