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You are here:Home » Antibodies » Abs to Infectious Disease Rotavirus » Anti -Rotavirus, ICP, Late Structural Virion Antigens (HRP)

Anti -Rotavirus, ICP, Late Structural Virion Antigens (HRP)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Purified E B IH
Rotaviruses, members of the family Reoviridae, are a major cause of diarrhea in young mammals. Human rotaviruses, the major etiological agents of severe infantile diarrhea worldwide, display very diverse and complex serotypic specificities. Rotaviruses are 70nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection. Therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
Catalog #R3000-12
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsELISA: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceBovine
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.5, 1% BSA, 0.005% thimerosal. Labeled with HRP.
PurityPurified
ImmunogenBovine (calf diarrhea virus)
SpecificityRecognizes human rotavirus: 95%. Specifc to ICP's and late structural (virons) antigens.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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