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You are here:Home » Antibodies » Abs to Infectious Disease Rotavirus » Anti -Rotavirus

Anti -Rotavirus

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IF
Rotaviruses, members of the family Reoviridae, are a major cause of diarrhea in young mammals.
Human rotaviruses, the major etiological agents of severe infantile diarrhea worldwide, display very diverse and complex serotypic specificities. Rotaviruses are 70nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection. Therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
Catalog #R3000-15A
ApplicationsSuitable for use in ELISA and IFA. Other applicaations not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Recommended PairCapture: R3000-15B
Detection: R3000-15A
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.    
Clone TypeMonoclonal
IsotypeIgG2b
Clone No9B123
HostMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in 0.01M PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein A chromatography. >90% pure.
ImmunogenPurified Rhesus Rotavirus (RRV).
SpecificityRecognizes the intact virus of strains RRV, WA, SA-11 and bovine. Immunostains infected cells. Does not react with Influenza A, Influenza B, RSV, Parainfluenza 1, 2 & 3, Adenovirus, M pneumonia, H. pylori and Mammalian cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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