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You are here:Home » Antibodies » Abs to Infectious Disease Rotavirus » Anti -Rotavirus Group Specific Antigen

Anti -Rotavirus Group Specific Antigen

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Rotavirus possesses a triple-layered icosahedral protein capsid; VP6 is the intermediate-layer protein and is the most immunogenic of the capsid proteins, although it doesn’t induce neutralising antibodies. Rotavirus is the leading cause of severe diarrhoea in young children and is responsible for a large number of deaths, particularly in developing countries, where sufferers will mostly die of dehydration.
Catalog #R3000-28A
This antibody is specific for mammalian group A rotaviruses (the most common group to infect humans) and cross-reacts with monkey rotavirus (SA-11), porcine rotavirus (PP) and numerous field strains of human rotaviruses.
ApplicationsSuitable for use in ELISA, Immunohistochemistry (frozen), and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10F389
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPurified bovine rotarvirus, cell culture adapted strain MR.
SpecificityRecognizes the p42 capsid antigen of rotavirus (the group-specific antigen, VP6). Specific for mammalian group A rotaviruses. Cross-reacts with monkey rotavirus (SA-11), porcine rotavirus (PP) and numerous field strains of human rotaviruses.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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