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You are here:Home » Antibodies » Abs to Enzymes, Glycosyltransferase » Anti -Radical fringe homolog (Beta-1,3-N-acetylglucosaminyltransferase radical fringe, O-fucosylpeptide-3-beta-N-acetylglucosaminyltransferase, RFNG)

Anti -Radical fringe homolog (Beta-1,3-N-acetylglucosaminyltransferase radical fringe,
O-fucosylpeptide-3-beta-N-acetylglucosaminyltransferase, RFNG)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IF
The Drosophila melanogaster 'fringe' gene is a secreted signaling protein that is involved in the formation of boundaries between groups of cells during development. It acts by modulating the activation of te Notch signal transduction pathway. A human radical fringe homolog was identified in 1997. There is evidence to show that radical fringe homolog may be involve in limb formation and in neurogenesis in humans. It is a glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. It is a single-pass type II membrane protein which localises to the golgi apparatus membrane. It belongs to the glycosyltransferase 31 family.
Catalog #R6038
ApplicationsSuitable for use in Immunofluorescence, ELISA and Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 10 ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G432
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant human radical fringe homolog (aa222-330) with a GST tag.
SpecificityRecognizes human radical fringe homolog.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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