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You are here:Home » Antibodies » Abs to Splicing Factors » Anti -SAP155 (SF3b155, Splicing factor 3b, Subunit 1, 155kDa, SAP155, Spliceosome associated protein 155, PRP10, PRPF10, Pre-mRNA processing factor 10)

Anti -SAP155 (SF3b155, Splicing factor 3b, Subunit 1, 155kDa, SAP155, Spliceosome
associated protein 155, PRP10, PRPF10, Pre-mRNA processing factor 10)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP
AP155 is a subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of the SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. It may also be involved in the assembly of the 'E' complex. SAP155 also belongs to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Catalog #S0096-23C
ApplicationsSuitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000-1:10,000
Immunoprecipitation: 2-5ug/mg lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in tris-buffered saline containing 0.1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a region between aa200 and 250.
SpecificityRecognizes human SAP155.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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