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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -SARM, CT (Sterile alpha and TIR Motif-containing Protein 1, SARM1, FLJ36296, KIAA0524, Sterile alpha and Armadillo Repeat Protein, Sterile alpha Motif Domain-containing Protein 2, SAM Domain-containing Protein 2, SAMD2, Tir-1 Homolog)

Anti -SARM, CT (Sterile alpha and TIR Motif-containing Protein 1, SARM1, FLJ36296,
KIAA0524, Sterile alpha and Armadillo Repeat Protein, Sterile alpha Motif
Domain-containing Protein 2, SAM Domain-containing Protein 2, SAMD2, Tir-1 Homolog)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IC IF
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-?B, andultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.
Catalog #S0097-70D
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 2ug/ml
Western Blot: 0.5-2ug/ml
Immunocytochemistry: 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlDaudi cell lysates.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human SARM (CT).
SpecificityRecognizes human SARM (CT). Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSterile alpha and TIR Motif Containing 1


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