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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -SARM1 (Sterile alpha and TIR Motif-containing Protein 1, Sterile alpha and Armadillo Repeat Protein, Sterile alpha Motif Domain-containing Protein 2, SAM Domain-containing Protein 2, Tir-1 homolog, KIAA0524, SAMD2, SARM)

Anti -SARM1 (Sterile alpha and TIR Motif-containing Protein 1, Sterile alpha and Armadillo
Repeat Protein, Sterile alpha Motif Domain-containing Protein 2, SAM Domain-containing
Protein 2, Tir-1 homolog, KIAA0524, SAMD2, SARM)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IP IH
Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.
Catalog #S0097-70F
ApplicationsSuitable for use in Immunohistochemistry and Immunoprecipitation.. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Immunoprecipitation: 1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone NoSarmy-1
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide, 10% glycerol.
PurityPurified
ImmunogenSynthetic peptide corresponding to human SARM1 conjugated to KLH.
SpecificityRecognizes human SARM1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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