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You are here:Home » Antibodies » Abs to Infectious Disease SARS » Anti -SARS, Spike Protein (Severe Acute Respiratory Syndrome, SARS-CoV, SARS Associated Coronavirus)

Anti -SARS, Spike Protein (Severe Acute Respiratory Syndrome, SARS-CoV, SARS Associated
Coronavirus)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome) (1-2). Coronaviruses are a major cause of upper respiratory diseases in humans (3). The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kD protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2 (4).
Catalog #S0098-36
ApplicationsCan be used for the detection of SARS Spike protein in ELISA. It will detect 10ng of free peptide at 1mg/ml.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRaised against a synthetic peptide corresponding to amino acids at the amino-terminus of the SARS Spike glycoprotein (Genbank accession no. P59594)
SpecificityRecognizes SARS Spike protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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