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You are here:Home » Antibodies » Antibodies-Receptors, Scavenger » Anti -Scavenger Receptor (SREC-I expressed by Endothelial Cells, Scavenger Receptor class F, member 1, SCARF1)

Anti -Scavenger Receptor (SREC-I expressed by Endothelial Cells, Scavenger Receptor class
F, member 1, SCARF1)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B FC
Scavenger Receptor expressed by Endothelial Cells (SREC-I), also known as Scavenger Receptor class F, member 1 (SCARF1) is expressed on endothelial cells, macrophages and phagocytic cells. It contains 6 EGF-like repeats in its extracellular domain. Besides binding scavenger receptor ligands such as fucoidin and acetylated LDL, SREC-I is an endocytic receptor for calreticulin and gp96. It also trans-interacts with SREC-II through the extracellular EGF repeats.
Catalog #S0098-98
ApplicationsSuitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.
Recommended DilutionDirect ELISA: 0.5-1.0ug/ml with the appropriate secondary reagents to detect human SREC-I. The detection limit for rhSREC-I is approximately 1ng/well and 100ng/ml under non-reducing and reducing conditons, respectively.
Flow Cytometry 0.25ug/ml. Use 10ul of the diluted antibody to stain 1x10e5 to 2.5 x 10e5 cells in a total reaction volume not exceeding 200ul. A fluorochrome-labeled secondary antibody such a goat anti-mouse IgG may be used for detection.
Western Blot 1-2ug/ml with the appropriate secondary reagents to detect human SREC-1. Using a colorimetric detection system, the detection limit for rhSREC-1 is approximately 1ng/lane and 100ng/lane under non-reducing and reducing conditions, respectively. Chemiluminescent detection will increase sensitivity by 5 to 50 fold.
Optimal dilutions should be determined by each laboratory for each application.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No8B43
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a powder lyophilized from a solution containing PBS with 5% trehalose. Reconstitute to 0.5mg/ml with 200ul of sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived recombinant protein comprising aa20-421 of human SREC-I (UniProt Accession #Q14162)
SpecificityRecognizes human SREC-I
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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