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You are here:Home » Antibodies » Abs to Receptors, Scavenger » Anti -Scavenger Receptor BI (Scavenger Receptor Class B Member 1, Scavenger Receptor Class B Type 1, Scavenging Receptor SR-BI, SCARB1, SRB1, SRBI, SR-BI, CD36 and LIMPII Analogous 1, CD36 Antigen-like 1, CD36L1, CLA1, CLA-1, Collagen Type I Receptor, MGC138242

Anti -Scavenger Receptor BI (Scavenger Receptor Class B Member 1, Scavenger Receptor Class
B Type 1, Scavenging Receptor SR-BI, SCARB1, SRB1, SRBI, SR-BI, CD36 and LIMPII Analogous
1, CD36 Antigen-like 1, CD36L1, CLA1, CLA-1, Collagen Type I Receptor, MGC138242

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IP IC IF N
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism.
In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Catalog #S0099-01C
ApplicationsSuitable for use in Neutralization, Immunocytochemistry, Immunofluorescence and Immunoprecipitation. For Western Blot use A4000-25B, S0099, or S0099-01D. Other applications not tested.
Recommended DilutiosnNeutralization: 1:500-1:1000 blocks binding of ligands to SR-BI.
Immunocytochemistry: 1:50-1:200
Immunofluorescence: 1:50-1:200
Immunoprecipitation: 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot Determined
FormSupplied as a liquid, 0.05% sodium azide.
PuritySerum
ImmunogenAdenovirus encoding mouse Scavenger Receptor BI
SpecificityRecognizes mouse Scavenger Receptor BI. Species crossreactivity: human. Blocks human SR-BI/Cla-1 (tested in HepG2 cells).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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