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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Sarcoglycan, delta (Delta-Sarcoglycan, Delta-SG, SGCD, SG-delta, SGD, SGCDP, 35kD Dystrophin-associated Glycoprotein, 35DAG, CMD1L, DAGD)

Anti -Sarcoglycan, delta (Delta-Sarcoglycan, Delta-SG, SGCD, SG-delta, SGD, SGCDP, 35kD
Dystrophin-associated Glycoprotein, 35DAG, CMD1L, DAGD)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH
Delta-Sarcoglycan is found in normal muscle but has a differential expression in certain instances of muscular dystrophy. This antibody will help identify the presence or absence of delta-sarcoglycan.
Catalog #S0160-01
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:25-1:50
Immunohistochemistry: 1:25-1:50 for 1 hr. at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Western Blot: Muscle specific band, or close doublet of bands, at around 35kD. In sarcoglycanopathy patients, both bands in the doublet may be lost, possibly corresponding to alternatively spliced products.
Immunohistochemistry: Normal human striated muscle frozen in isopentane chilled in liquid nitrogen. Staining pattern continuous staining around normal mus- cle fibre membranes. Less or no staining is observed in patients with LGMD2F (depending on mutations).
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone NoDSarc3/12C1
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS, 1% BSA, 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenSynthetic peptide including residues 1-19 at the amino-terminus of the human d-sarcoglycan sequence.
SpecificityRecognizes human Delta-Sarcoglycan.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSarcoglycan, delta (35kDa Dystrophin-associated Glycoprotein)


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