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Abs to Cell Division Cycle (CDC)
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Anti -Securin (Esp1-associated Protein, EAP1, Pituitary Tumor-transforming Gene 1 Protein, PTTG1, PTTG, hPTTG, Tumor-transforming Protein 1, TUTR1)
Anti -Securin (Esp1-associated Protein, EAP1, Pituitary Tumor-transforming Gene 1 Protein,
PTTG1, PTTG, hPTTG, Tumor-transforming Protein 1, TUTR1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
IH |
|
| Human securin is also referred to as pituitary tumor- transforming gene-1. It is required for chromosomal stability in human cells for the maintenance of euploidy. Its expression correlates with cell proliferation in a cellcycle dependent manner in normal tissues and several tumor types. Human securin binds to Ku, the controlling subunit of the DNA-dependent protein kinase. This antibody will help detect human securin and further characterize its expression in various tissues. | | | Catalog # | S0379-80E | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 1:25-1:50 for 1 hr. at RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | | | Tonsil (cytoplasmic and nuclear staining pattern) | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a,k | | Clone No | DCS-280.2 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O. | | Purity | Supernatant | | Immunogen | Recombinant fusion protein representing the GST-Pds1 of the human securin molecule. | | Specificity | Recognizes human Securin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Pituitary Tumor-transforming 1 |
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