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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -Securin (Esp1-associated Protein, EAP1, Pituitary Tumor-transforming Gene 1 Protein, PTTG1, PTTG, hPTTG, Tumor-transforming Protein 1, TUTR1)

Anti -Securin (Esp1-associated Protein, EAP1, Pituitary Tumor-transforming Gene 1 Protein,
PTTG1, PTTG, hPTTG, Tumor-transforming Protein 1, TUTR1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Human securin is also referred to as pituitary tumor- transforming gene-1. It is required for chromosomal stability in human cells for the maintenance of euploidy. Its expression correlates with cell proliferation in a cellcycle dependent manner in normal tissues and several tumor types. Human securin binds to Ku, the controlling subunit of the DNA-dependent protein kinase. This antibody will help detect human securin and further characterize its expression in various tissues.
Catalog #S0379-80E
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:25-1:50 for 1 hr. at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Tonsil (cytoplasmic and nuclear staining pattern)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone NoDCS-280.2
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenRecombinant fusion protein representing the GST-Pds1 of the human securin molecule.
SpecificityRecognizes human Securin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPituitary Tumor-transforming 1


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