SCF, Recombinant, Human (Stem Cell Factor, Stem Cell Factor Precursor, c-Kit Ligand,
DKFZp686F2250, KIT Ligand, KitL, KITLG, KL-1, Mast Cell Growth Factor, MGF, Steel Factor,
SF)
Pricing
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| Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117 (c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. | | | SCF is a growth factor important for the survival, proliferation and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid). | | | Catalog # | S0400-07P | | Amino Acid Sequence | The sequence of the first five amino acids was determined to be Met-Glu-Gly-Ile-Cys | | | | Biological Activity: | | The ED50 as determined by the dose-dependent stimulation of Human TF-1 cells is <2ng/ml, corresponding to a Specific Activity of 5x10e5IU/mg. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 18.4kD | | Source | Human recombinant SCF, produced in E. coli, is a single, non-glycosylated polypeptide chain containing 165 amino acids. | | Purity | Purified by chromatography. | | Concentration | ~0.1mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from 10mM acetic acid. Reconstitute with 20ul sterile ddH2O. For long term storage, add a carrier protein (0.1% HSA or BSA). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for SCF, Recombinant, Human (Stem Cell Factor, Stem Cell Factor Precursor, c-Kit Ligand, DKFZp686F2250, KIT Ligand, KitL, KITLG, KL-1, Mast Cell Growth Factor, MGF, Steel Factor, SF) |
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