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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -SCAMP3 (secretory carrier membrane protein 3, "Propin 1", C1orf3, PROPIN1, Secretory carrier-associated membrane protein 3, Secretory carrier membrane protein 3)

Anti -SCAMP3 (secretory carrier membrane protein 3, "Propin 1", C1orf3, PROPIN1, Secretory
carrier-associated membrane protein 3, Secretory carrier membrane protein 3)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Affinity Purified B
SCAMP3 (Secretory carrier membrane protein 3) is a 38-40kD member of the SCAMP
family of proteins. It is expressed in heart and skeletal muscle, plus fat, and functions in
post-Golgi recycling and EGFR internalization pathways. Human SCAMP3 is 347aa in length. It contains a cytoplasmic N-terminus (aa1-170) that shows three NPF repeats (binding sites for EH domain proteins), a heptad repeat of aliphatic aas, and a potential SH3-binding motif. This is followed by four consecutive transmembrane domains (aa171-297) plus a C-terminal cytoplasmic region (aa298-347). It appears that phosphorylation of SCAMP3 on Tyr41 is a requisite for its interaction with EGFR. There are three potential splice forms. One shows a deletion of aa 23-48, while two others show a one and 23 aa substitution for aa131-144 and 131-260, respectively. Over aa1-170, human and mouse SCAMP3 are 91% aa identical.
Catalog #S0442-01C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human SCAMP3, aa1- 170; O14828 (E. coli).
SpecificityRecognizes human/mouse SCAMP3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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