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You are here:Home » Antibodies » Abs to Chromogranin » Anti -Secretogranin-5 (Neuroendocrine protein 7B2, Secretory granule endocrine protein I, Secretogranin V, Pituitary polypeptide, SCG5, SGNE1)

Anti -Secretogranin-5 (Neuroendocrine protein 7B2, Secretory granule endocrine protein I,
Secretogranin V, Pituitary polypeptide, SCG5, SGNE1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Secretogranin-5 is an acidic protein of 186aa and has an expression that seems to be restricted to neurons and endocrine cells. In the brain, it is most abundant in the supraoptic and paraventricular nuclei of the hypothalamus. It acts in neuroendocrine cells as a specific chaperone for proprotein convertase-2 (PC2) which is an important endoprotease involved in the processing of neuroendocrine precursors. It binds to inactive proPC2 in the ER and facilitates its movement toward the secretory pathway where proPC2 is proteolytically matured and activated. It also plays a role in regulating pituitary hormone secretion.
Catalog #S0626-05
ApplicationsSuitable for use in Direct ELISA and Western Blot. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG
Clone No9G437
HostMouse
SourceHuman
Concentration~1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenPartial recombinant protein corresponding to aa59-160 of human Secretogranin-5 with a GST tag.
SpecificityRecognizes human Secretogranin-5. Species Crossreactivity: mouse and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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