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You are here:Home » Antibodies » Abs to Chromogranin » Anti -Secretogranin-5 (Secretogranin 5, SCG5, Secretogranin V, SgV, 7B2, Neuroendocrine Protein 7B2, P7B2, Pituitary Polypeptide, Secretory Granule Endocrine Protein I, SGNE1)

Anti -Secretogranin-5 (Secretogranin 5, SCG5, Secretogranin V, SgV, 7B2, Neuroendocrine
Protein 7B2, P7B2, Pituitary Polypeptide, Secretory Granule Endocrine Protein I, SGNE1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH IF
Secretogranin-5 is an acidic protein of 186aa and has an expression that seems to be restricted to neurons and endocrine cells. In the brain, it is most abundant in the supraoptic and paraventricular nuclei of the hypothalamus. It acts in neuroendocrine cells as a specific chaperone for proprotein convertase-2 (PC2) which is an important endoprotease involved in the processing of neuroendocrine precursors. It binds to inactive proPC2 in the ER and facilitates its movement toward the secretory pathway where proPC2 is proteolytically matured and activated. It also plays a role in regulating pituitary hormone secretion.
Catalog #S0626-05C
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionsWestern Blot: 1:500 detected Secretogranin-5 in rat brain tissue.
Immunofluorescence: 1:200
Immunohistochemistry (PAP or ABC): 1:500
Optimal dilutions to be determined by the researcher.
Amino Acid SequenceGlu-Phe-Gly-Leu-Gln-Leu-His-Gln-His-Leu-Phe-Asp-Pro-Glu-His -Asp-Tyr-Pro-Gly-Lys-Trp-Asn-Lys-Lys-Leu-Leu-Tyr-Glu-Lys-Met -Lys-Gly-Gly-Gln
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourcePorcine
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa126-159 from porcine Secretogranin-5.
SpecificityRecognizes porcine Secretogranin-5. Species Crossreactivity: human, rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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