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You are here:Home » Antibodies » Abs to Plexin, Semaphorin » Anti -Semaphorin 3E (Semaphorin-3E, SEMA3E, KIAA0331, SEMAH)

Anti -Semaphorin 3E (Semaphorin-3E, SEMA3E, KIAA0331, SEMAH)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified IH
Semaphorin 3E (previously SemaH) is a secreted protein belonging to the semaphorin family. Semaphorin 3E is highly expressed by a subset of motor neurons in developing somites, where it acts as a repulsive cue for PlexinD1-expressing endothelial cells of adjacent intersomitic vessels. Like other Semaphorin 3 proteins, the 775 aa human Semaphorin 3E contains a signal sequence, a Semaphorin domain, a C2-like Ig domain and a C-terminal basic domain. Disulfide-linked dimerization and furin-type proteolytic processing increase Semaphorin 3E bioactivity. Mature human and mouse Semaphorin 3E share 90% aa identity.
Catalog #S0668-50F
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 2-4ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Breast lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KPEHYRLPRHTLDS, from the C-terminus of the protein sequence according to NP_036563.
SpecificityRecognizes human Semaphorin 3E.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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