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You are here:Home » Antibodies » Abs to Plexin, Semaphorin » Anti -SEMA3E (Semaphorin-3E, KIAA0331, SEMAH)

Anti -SEMA3E (Semaphorin-3E, KIAA0331, SEMAH)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E IH
Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation.
Catalog #S0668-50L
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Immunohistochemistry (Paraffin): 4-6ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-NGGRYGTTKDYPDD, from human SEMA3E, at the internal region of the protein (NP_036563.1, NP_001171600.1).
SpecificityRecognizes human SEMA3E. Species sequence homology: Canine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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