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You are here:Home » Antibodies » Abs to Enzymes, ATPase » Anti -SERCA1 (Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 1, SERCA 1 ATPase, SR Ca(2+) ATPase 1, ATPase Ca++ Transporting Cardiac Muscle Fast Twitch 1, ATPase Ca++ Transporting Fast Twitch 1, ATP2A, ATP2A1, Calcium Pump 1, Calcium Transporting ATPase Sarc

Anti -SERCA1 (Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 1, SERCA 1 ATPase, SR
Ca(2+) ATPase 1, ATPase Ca++ Transporting Cardiac Muscle Fast Twitch 1, ATPase Ca++
Transporting Fast Twitch 1, ATP2A, ATP2A1, Calcium Pump 1, Calcium Transporting ATPase
Sarc

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Sarcoplasmic and endoplasmic reticulum Ca2+ ATPases (SERCA) are members of a highly conserved family of Ca2+ pumps (1). SERCA pumps transport Ca2+ from the cytosol to the sarcoplasmic and endoplasmic reticulum lumen against a large concentration gradient (1). ATP2A1 (SERCA1) is a fast-twitch, skeletal muscle sarcoplasmic reticulum Ca2+ ATPase (2). Mutations in the correspond-ing gene cause an autosomal recessive muscle disorder known as Brody myopathy, which is characterized by muscle cramping and impaired muscle relaxation associated with exercise (1-3).
Applications:
Suitable for use in Western Blot. Other applications not tested.
Catalog #S0976-40B
Recommended DilutionWestern Blot: 1:1000 Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceMouse
ConcentrationNot determined
FormSupplied as a liquid in 10mM sodium HEPES pH 7.5, 0.1%, 150mM NaCl, 100ug/ml BSA and 50% glycerol.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide derived from the sequence around Ala988 of mouse ATP2A1/SERCA1 protein (KLH-coupled).
SpecificityRecongnizes endogenous levels of mouse total ATP2A1/SERCA1 protein. Species crossreactivity: rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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