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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -Cortisol Binding Globulin (CBG, Corticosteroid Binding Globulin, SERPINA6, Serine or Cysteine Proteinase Inhibitor Clade A, alpha-1 Antiproteinase, alpha-1 Antiproteinase, Transcortin)

Anti -Cortisol Binding Globulin (CBG, Corticosteroid Binding Globulin, SERPINA6, Serine or
Cysteine Proteinase Inhibitor Clade A, alpha-1 Antiproteinase, alpha-1 Antiproteinase,
Transcortin)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Serpin A6 (also known as corticosteroid-binding globulin/CBG and Transcortin) is a 50-60kD, secreted glycoprotein member of the serpin family of protease inhibitors. It is produced by hepatocytes and transports >90% of circulating cortisol. Although Serpin A6 is a serpin family member, it shows no protease inhibition. Mature mouse Serpin A6 is 375aa in length.
Catalog #S1000-76Z
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Direct ELISA. Other applications not tested.
Recommended DilutionsWestern Blot: 0.1-0.2ug/ml detects mouse Serpin 6. Detection limit for recombinant mouse Serpin 6 is ~0.5ng/ml under non-reducing and reducing conditions.
Immunohistochemistry: 5-15ug/ml detects mouse Serpin 6 in cells and tissues.
Direct ELISA: 0.5-1ug/ml detects mouse Serpin 6. Detection limit for recombinant mouse Serpin 6 is ~0.5ng/well
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
Concentration~0.2mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
PurityPurified by Immunoaffinity chromatography.
ImmunogenRecombinant corresponding to aa23-397 from mouse Serpin A6, expressed in NSO cells (Accession # Q06770). Species Sequence Homology: rat; 78% and human; 57%.
SpecificityRecognizes mouse Serpin A6. Shows ~25% crossreactivty with recombinant rat Serpin A6 and <1% crossreactivity with recombinant human Serpin A1 and recombinant human Serpin A5 when tested in Direct ELISA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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