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You are here:Home » Antibodies » Antibodies-Protease Inhibitors » Anti -SERPINB8 (Serine/Cysteine Proteinase Inhibitor, Clade B, Member 8, NK10, PI8)

Anti -SERPINB8 (Serine/Cysteine Proteinase Inhibitor, Clade B, Member 8, NK10, PI8)


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Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IP
Serpin B8 (serine proteinase inhibitor-clade B #8; also NK10) is a 42-45 kD, cytoplasmic and secreted member of the ovalbumin (clade B)-subfamily, Serpin superfamily of protease inhibitors. It is produced by multiple cell types and shows inhibitory activity towards furin and possibly other proteinases such as chymotrypsin. Mouse Serpin B8 is 374 amino acids (aa) in length. Although it has no signal sequence, it is likely to be released by platelets. The active inhibitory site lies between Arg336 and Arg342. One potential isoform shows a 4 aa substitution for the C-terminal 133 amino acids. Full length mouse Serpin B8 shares 78% and 91% aa identity with human and rat Serpin B8, respectively.
Catalog #S1000-77N1
ApplicationsSuitable for use in Immunoprecipitation, Western Blot and ELISA. Other applications not tested.
Recommended DilutionWestern Blot: 0.1-0.2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile ddH2O or sterile 40-50% glycerol.
PurityPurified by mouse Serpin B8 affinity chromatography.
ImmunogenSf21-derived recombinant mouse serpin B8 (aa2-374) Accession # O08800
SpecificityRecognizes mouse Serpin B8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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