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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified B

Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as brinolysis, coagulation, in ammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular uids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. Differential display was used to identify a novel serpin (headpin or SERPIN B13) that is underexpressed in squamous cell cancers of the oral cavity. SERPIN B13 is expressed in normal oral mucosal tissue, skin, and cultured keratinocytes.
Catalog #	S1000-92
Applications	Suitable for use in Western Blot. Other applications have not been tested.
Recommended Dilution	Western Blot: 1:250-1:500
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Human
Concentration	~0.5mg/ml
Form	Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide before the addition of 40% glycerol.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Synthetic peptide, aa310–324 of the human SERPIN B13 protein.
Specificity	Reacts with residues 310–324 of the human SERPIN B13 protein.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.