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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -SERPINI1 (Peptidase Inhibitor 12, PI-12, Serpin I1, Neuroserpin, PI12)

Anti -SERPINI1 (Peptidase Inhibitor 12, PI-12, Serpin I1, Neuroserpin, PI12)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Catalog #S1000-95G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 1-3ug/ml, observed in human brain lysate on ~48kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-TMNTSGHDFEEL, from human SERPINI1, at C-terminal (NP_005016.1).
SpecificityRecognizes human SERPINI1. Species sequence homology: Bovine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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