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You are here:Home » Antibodies » Abs to Serotonin Receptors » Anti -Serotonin Receptor 1A

Anti -Serotonin Receptor 1A

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified B IH
Serotonin Receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin Receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin Receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.
Catalog #S1001-15C
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 0.5ug/ml detects Serotonin Receptor 1A on 10ug of rat brain tissue lysate. Band is observed at ~40kD. Calculated MW is 46kD.
Immunohistochemistry: 1:400 detects Serotonin Receptor 1A in normal human brain tissue.
Optimal dilutions to be determined by the researcher.
Positive ControlRat brain tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM,k
Clone No11C254
HostMouse
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide.
PurityPurified by ion exchange chromatography.
ImmunogenLinear peptide corresponding to rat Serotonin Receptor 1A, conjugated to KLH ( NP_036717).
SpecificityRecognizes rat Seratonin receptor 1A. Species Crossreactivity: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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