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You are here:Home » Antibodies » Abs to Serotonin Receptors » Anti -Serotonin Receptor 1B (5-Hydroxytryptamine (Serotonin) Receptor 1B, 5-Hydroxytryptamine Receptor 1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1B Receptor, 5-HT1DB, HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta Receptor)

Anti -Serotonin Receptor 1B (5-Hydroxytryptamine (Serotonin) Receptor 1B,
5-Hydroxytryptamine Receptor 1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1B Receptor, 5-HT1DB,
HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta Receptor)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythm light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches. Human 5HT1B shares 92% aa sequence identity with mouse and rat 5HT1B.
Catalog #S1001-19C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Paraffin): 25ug/ml detected Serotonin Receptor 1B in normal human brain cortex and glia tissue sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9i139
HostMouse
SourceHuman
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified human Serotonin Receptor 1B transfected NS0 cells (Accession #P28222).
SpecificityRecognizes human Serotonin Receptor 1B. Species Sequence Homology: mouse and rat; 92%.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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