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You are here:Home » Antibodies » Abs to Serotonin Receptors » Anti -Serotonin Receptor 3A (5-HT3A, 5-HT3-A, HTR3A, 5-Hydroxytryptamine (Serotonin) Receptor 3A, 5-Hydroxytryptamine Receptor 3, 5HT3, 5-HT-3, 5-HT3R, HTR3, Serotonin-gated Ion Channel Receptor)

Anti -Serotonin Receptor 3A (5-HT3A, 5-HT3-A, HTR3A, 5-Hydroxytryptamine (Serotonin)
Receptor 3A, 5-Hydroxytryptamine Receptor 3, 5HT3, 5-HT-3, 5-HT3R, HTR3, Serotonin-gated
Ion Channel Receptor)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
5HT are receptors for neurotransmitter and peripheral signal mediator serotonin. It is also known as 5-hydroxytryptamine or 5HT. 5HT receptors mediate the effects of serotonin as the endogenous ligand and of a broad range of pharmaceutical and hallucinogenic drugs. Specifically, 5HT receptors affect the release of other neurotransmitters such as glutamate, dopamine, and GABA as well as their activities. 5HT2A is a type of receptor that belongs to the serotonin receptor family and is one member of G protein coupled receptor (GPCR) family. 5HT2A is involved in the contraction of tracheal smooth muscle, bronchoconstriction, and the control of aldosterone production. The receptor also happens to be necessary for the spread of the human polyoma virus called JC virus. 5HT2A is widely expressed throughout the central nervous system (CNS). It is expressed near most of the serotoninergic terminal rich areas, including neocortex and olfactory tubercle. Increased stimulation of 5HT2A receptors seems to oppose the therapeutic actions of increased stimulation of other serotonin receptors in anti-depressant and anxiolytic treatments.
Catalog #S1001-19Q
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Western Blot: 0.3-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-GPQDFEKSPRDR from an internal region of human HTR3A.
SpecificityRecognizes human HTR3A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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