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Anti -Sarcoglycan, Gamma (SGCG Sarcoglycan, Gamma (35kDa Dystrophin-Associated Glycoprotein))
Anti -Sarcoglycan, Gamma (SGCG Sarcoglycan, Gamma (35kDa Dystrophin-Associated
Glycoprotein))
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). | | | Catalog # | S1009-25 | | Applications | Suitable for use in ELISA. Other applications have not been tested. | | Recommended Dilutions | | | Peptide ELISA Titer: 1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by peptide affinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-NQQFQINSNDGKP, from the internal region of human NP_000222.1. | | Specificity | Recognizes gamma sarcoglycan. Species sequence homology: human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | sarcoglycan, gamma (35kD dystrophin-associated glycoprotein), limb girdle muscular dystrophy 2C (Duchenne-like muscular dystrophy, autosomal recessive), gamma sarcoglycan, OTTHUMP00000018112, Maghrebian myopathy (autosomal recessive), 35kD dystrophin-asso |
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