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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -SETDB1 (Histone H3-K9 Methyltransferase 4, H3-K9-HMTase 4, SET Domain Bifurcated 1, ERG-associated Protein with SET Domain, Histone-lysine N-methyltransferase SETDB1, Lysine N-methyltransferase 1E, ESET, KIAA0067, KMT1E)

Anti -SETDB1 (Histone H3-K9 Methyltransferase 4, H3-K9-HMTase 4, SET Domain Bifurcated 1,
ERG-associated Protein with SET Domain, Histone-lysine N-methyltransferase SETDB1, Lysine
N-methyltransferase 1E, ESET, KIAA0067, KMT1E)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
The SET domain is a highly conserved, approximately 150aa motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.
Catalog #S1010-68F
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2500
ELISA: 1:10,000-1:50,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1058-1075 of human SETDB1 (KLH).
SpecificityRecognizes human SETDB1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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