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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -SETMAR (Histone-lysine N-methyltransferase SETMAR, SET Domain and Mariner Transposase Fusion Gene-containing Protein, HsMar1, Metnase)

Anti -SETMAR (Histone-lysine N-methyltransferase SETMAR, SET Domain and Mariner
Transposase Fusion Gene-containing Protein, HsMar1, Metnase)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA.
Catalog #S1012-30C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 1-3ug/ml, Daudi lysate observed on ~70-75kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to RWQKCVDCNGSYFD, from human SETMAR, at C-terminal (NP_006506.3).
SpecificityRecognizes human SETMAR. Species sequence homology: Bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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