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You are here:Home » Antibodies » Antibodies-Wnt Proteins » Anti -SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human Endometrium, FrpHE)

Anti -SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human
Endometrium, FrpHE)


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Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
Catalog #S1012-89C
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionELISA (Peptide): 1:32,000
Western Blot: 1-3ug/ml detects a band at ~40kD in human uterus lysates
Immunohistochemistry (Paraffin): 2-4ug/ml using paraffin embedded human uterus shows grandular staining in the apical cytoplasm of the endometrial gland
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa TNSSCQCPHILPHQD, from an internal region of human SFRP4 (NP_003005.2).
Species sequence homologyBovine, mouse, porcine and rat.
SpecificityRecognizes human SFRP4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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