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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human Endometrium, FrpHE)

Anti -SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human
Endometrium, FrpHE)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
Catalog #S1012-89C
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 0.3-1ug/ml, observed in human uterus lysates on ~40kD bands
Immunohistochemistry (Paraffin): 4-6ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to TNSSCQCPHILPHQD, from human SFRP4, at the internal region of the protein (NP_003005.2).
SpecificityRecognizes human SFRP4. Species sequence homology: Bovine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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