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You are here:Home » Antibodies » Abs to Signal Transduction » Anti -SH3BP1 (SH3-domain Binding Protein 1, 3BP-1, dJ37E16, FLJ21318, OTTHUMP00000028981)

Anti -SH3BP1 (SH3-domain Binding Protein 1, 3BP-1, dJ37E16, FLJ21318, OTTHUMP00000028981)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to c-Abl proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).
Catalog #S1013-31F
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Positive Control Normal human kidney and lung.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: PQPRPRSLASETN representing the C-Terminus of the human protein (residues 689-701) according to NP_061830.
SpecificitySpecies Crossreactivity: Crossreacts with Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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