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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Sialoprotein, Bone (BSP)

Anti -Sialoprotein, Bone (BSP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E IH
Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.
Catalog #S1013-32
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1000
Immunohistochemistry (paraffin sections): 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. No preservative added. Reconstitute with 20ul sterile ddH2O or 40-50% glycerol.
PurityNeat serum
ImmunogenSynthetic peptide from human Bone Sialoprotein (aa39-47, LKRFPVQGG).
SpecificitySpecific for human Bone Sialoprotein, aa39-47.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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