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You are here:Home » Antibodies » Antibodies-Extracellular Matrix Proteins » Anti -Sialoprotein, Bone (BSP)

Anti -Sialoprotein, Bone (BSP)


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Clone Host Grade Applications
Polyclonal Rabbit Serum E B IH RIA
Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an MW ~70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.
Catalog #S1013-34A
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, RIA and ELISA. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: 1:2500 using 5um paraffin embedded sections from human fetal tibia, fetal calvaria and metastatic breast tumors to bone; with decalcification with 10% formic acid
Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies IHC
I1904-43: IgG, X-Adsorbed (Biotin) Pab GtxRb
I1904-40E: IgG, H&L (Biotin) Pab GtxRb
I1904-46P: IgG, H&L (Biotin) Pab GtxRb
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
ConcentrationNot Determined
FormSupplied as a liquid. No preservatives added.
ImmunogenPurified human Bone sialoprotein
SpecificityRecognizes human Bone sialoprotein (BSP). Does not crossreact with human osteopontin or osteonectin by RIA or ELISA. Species Crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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