Anti -Sialoprotein, Bone, CT (BSP, BSP-1, OPN, Bone Sialoprotein I, Secreted
Phosphoprotein 1, SPP1, Early T-Lymphocyte Activation 1) )
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH IC |
|
| Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations, as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling. | | | Catalog # | S1013-34B | | Applications | Suitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. Other applications have not been tested. | | Recommended Dilution | Western Blot: 1:1000 | | Immunohistochemistry: Paraffin embedded sections | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human osteoblasts or osteocytes | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.- | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2Q556 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder from 50mM Tris, pH 7.4, 0.04% Thirmerosal, 0.1% sodium azide. Reconstitute with 100ul sterile 40-50% glycerol ddH2O. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Purified Human Bone Sialoprotein. | | Specificity | Recognizes Human Bone Sialoprotein (BSP), C-terminal portion. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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