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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Sialoprotein, Bone, CT (BSP, BSP-1, OPN, Bone Sialoprotein I, Secreted Phosphoprotein 1, SPP1, Early T-Lymphocyte Activation 1) )

Anti -Sialoprotein, Bone, CT (BSP, BSP-1, OPN, Bone Sialoprotein I, Secreted
Phosphoprotein 1, SPP1, Early T-Lymphocyte Activation 1) )

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IC
Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations, as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.
Catalog #S1013-34B
ApplicationsSuitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry: Paraffin embedded sections
Optimal dilutions to be determined by the researcher.
Positive ControlHuman osteoblasts or osteocytes
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.-
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q556
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder from 50mM Tris, pH 7.4, 0.04% Thirmerosal, 0.1% sodium azide. Reconstitute with 100ul sterile 40-50% glycerol ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified Human Bone Sialoprotein.
SpecificityRecognizes Human Bone Sialoprotein (BSP), C-terminal portion.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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