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Specifications

Clone Host Grade Applications Polyclonal Rabbit Serum E B IH RIA

Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.
Catalog #	S1013-34G
Applications
	Suitable for use in RIA, ELISA, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended Dilutions	Immunohistochemistry: paraffin sections
	Optimal dilutions to be determined by the researcher.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Host	Rabbit
Source	Human
Concentration	Not determined
Form	Supplied as a lyophilized powder. Reconstitute with 20ul ddH2O.
Purity	Serum
Immunogen	Human bone sialoprotein (bone extract)
Specificity	Recognizes human bone sialoprotein. Species Crossreactivity: rat. No cross reactivity with human Osteonectin or human Osteopontin.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.