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Abs to Extracellular Matrix Proteins
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Anti -Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein, Integrin-binding Sialoprotein)
Anti -Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein,
Integrin-binding Sialoprotein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Chicken |
Serum |
E B IH FC RIA |
|
| Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling. | | | Catalog # | S1013-34P | | Applications | Suitable for use in ELISA, Western Blotting. Other applications not tested. | | Recommended Dilution | ELISA: 1ug/ml | | RIA: 20ng/ml | | Flow Cytometry: 2ng/ml | | Immunohistochemistry: 1:100. Paraffin | | Western Blotting: 1:1000-1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgY | | Host | Chicken | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute in ddH2O. | | Purity | Serum | | Immunogen | Human Bone Sialoprotein (bone extract) | | Specificity | Recognizes human Bone Sialoprotein (native protein). There were no cross reactivities obtained with human Osteonectin, human Osteopontin and human Alkaline Phosphatase. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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