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Abs to Extracellular Matrix Proteins
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Anti -Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein, Integrin-binding Sialoprotein)
Anti -Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein,
Integrin-binding Sialoprotein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH IC RIA |
|
| Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling. | | | Catalog # | S1013-36A | | Applications | Suitable for use in ELISA, Western Blot, Immunohistochemistry, RIA, Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin and frozen): 1:100 | | Immunocytochemistry: 1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | ID1.2 | | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder in 50mM Tris, pH 7.2. Reconstitute with 10ul sterile ddH2O. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Human Bone Sialoprotein (Bone extract). | | Specificity | Recognizes human Bone Sialoprotein and recombinant human BSP. There were no cross reactivities obtained with bovine BSP, porcine BSOP, rat BSP, human Osteonectin and human Osteopontin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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