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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein, Integrin-binding Sialoprotein)

Anti -Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein,
Integrin-binding Sialoprotein)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IC RIA
Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.
Catalog #S1013-36A
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry, RIA, Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin and frozen): 1:100
Immunocytochemistry: 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoID1.2
HostMouse
SourceHuman
Concentration~1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder in 50mM Tris, pH 7.2. Reconstitute with 10ul sterile ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman Bone Sialoprotein (Bone extract).
SpecificityRecognizes human Bone Sialoprotein and recombinant human BSP. There were no cross reactivities obtained with bovine BSP, porcine BSOP, rat BSP, human Osteonectin and human Osteopontin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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