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You are here:Home » Antibodies » Abs to Lectins » Anti -Siglec 5, NT (Sialic Acid-binding Ig-like Lectin 5, Siglec 5, Obesity-binding Protein 2, OB-binding Protein 2, OB-BP2, CD33 Antigen-like 2, CD170, CD33L2, OBBP2)

Anti -Siglec 5, NT (Sialic Acid-binding Ig-like Lectin 5, Siglec 5, Obesity-binding
Protein 2, OB-binding Protein 2, OB-BP2, CD33 Antigen-like 2, CD170, CD33L2, OBBP2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation.
Catalog #S1013-59
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human SIGLEC5 (KLH).
SpecificityRecognizes human SIGLEC5. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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